Desloratadine is a purified single isomer version of loratadine, which contains a mixture of active and inactive isomers.
In this way desloratadine is designed to have even less side effects than loratadine because it only uses the therapeutically-active isomer.
Each of the second generation antihistamines may be more suited to treating some conditions rather than others.
For example, cetirizine can be more effective at relieving allergy symptoms, especially controlling itching and swelling.
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In some cases, however, individuals with a low threshold for the medication may find they experience slight sleepiness after taking them or after taking a higher than recommended dose.
The mast cells that are spread throughout the tissues of the body release histamine as part of their defence mechanism against the foreign substance but the reaction usually remains localised.
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